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is a city in Calhoun and Talladega counties in the U.S. state of Alabama. The population was 14,592 at the 2000 census. Oxford is one of two principal cities of and included in the Anniston-Oxford Metropolitan Statistical Area.
According to the U.S. Census Bureau, the city has a total area of 18.3 square miles (47.4 km²), of which, 18.2 square miles (47.2 km²) of it is land and 0.1 square miles (0.2 km²) of it (0.38%) is water.
Oxford lies among the foothills at the southern end of the Blue Ridge mountains. Nearby Mount Cheaha is Alabama's highest point and offers expansive views of the surrounding wilderness and the city below. Much of the city's southern border is shared with the Talladega National Forest.
Major bodies of water include Oxford Lake, Lake Hillabee, and Choccolocco Creek, which bisects the city.