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is a town in Santa Cruz County, Arizona, United States. According to 2006 Census Bureau estimates, the population of the town is 825. Patagonia was formerly a supply center for nearby mines and ranches. Currently, it is a tourist destination, retirement community and arts & crafts center. National and state authorities have recognized Patagonia Union High School as one of the best schools in the state. The Nature Conservancy's Patagonia-Sonoita Creek Preserve is adjacent.
According to the United States Census Bureau, the town has a total area of 1.2 square miles (3.1 km²), all of it land.