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is a city in Madison County, Iowa, United States. The population was 619 at the 2000 census. It is part of the Des Moines–West Des Moines Metropolitan Statistical Area.
St. Charles is located at (41.287857, -93.807982).
According to the United States Census Bureau, the city has a total area of 0.6 square miles (1.5 km²), all of it land.