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is a town in Huntington and Wells Counties in the U.S. state of Indiana. The population was 1,102 at the 2000 census. It lies along Indiana State Road 3 and U.S. Route 224.
Markle is located at (40.826477, -85.338076). The Wabash River flows through the south edge of the town.
According to the United States Census Bureau, the town has a total area of 1.0 square miles (2.6 km²), of which, 1.0 square miles (2.6 km²) of it is land and 0.04 square miles (0.1 km²) of it (2.94%) is water.