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is a village in Genesee County in the U.S. state of Michigan. The population was 366 at the 2000 census. The village is within Gaines Township.
The Village of Gaines did not see a settler until 1856. The first passenger train passed through the future village site on July 4, 1856 and a post office was established that same year. The Grand Trunk Western Railroad depot, built in 1884, now houses a library branch.