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is a small city in Callaway County, Missouri, United States. The population was 188 at the 2000 census. It is part of the Jefferson City, Missouri Metropolitan Statistical Area.
Mokane is located at (38.676041, -91.874404). It is located on the north bank of the Missouri River at mile 123.4. The Katy Trail, a rails-to-trails hiking/biking path, runs through the town, which stands at mile 125. According to the United States Census Bureau, the city has a total area of 0.3 square miles (0.8 km²), all of it land.