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is a town in Monroe County, Mississippi, United States. The population was 882 at the 2000 census. Smithville was the birthplace of Rod Brasfield, a member of the Country Music Hall of Fame.
According to the United States Census Bureau, the town has a total area of 1.6 square miles (4.1 km²), of which, 1.5 square miles (3.8 km²) of it is land and 0.1 square miles (0.3 km²) of it (8.12%) is water.