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is a town in Orange County, North Carolina, United States. The population was 5,446 at the 2000 census. It is the county seat of Orange County.
Its name was unofficially shortened to "Hillsboro" over the years (beginning in the 19th century) but was changed back to its original spelling in the late 1960s.
According to the United States Census Bureau, the town has a total area of 4.6 square miles (11.9 km²), of which, 4.6 square miles (11.9 km²) of it is land and 0.22% is water.