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is a city in the U.S. state of North Carolina. Winston-Salem is the county seat and largest city of Forsyth County and the fourth-largest city in the state. Winston-Salem is a prominent municipality in the Piedmont Triad region and is home to some of the tallest office buildings in the region, such as the Wachovia Center. It is called the "Twin City" for its dual heritage, or "Camel City", a reference to Camel cigarettes and the city's prominent tobacco industry; locals use "Winston" in informal speech. Winston-Salem is home to two universities: Wake Forest University, a nationally distinguished private university and Winston-Salem State University, an HBCU founded in 1892.
The Old Salem district and related Historic Bethabara site are the city's oldest
historical attractions. Also of historical interest is Reynolda Village (which includes Reynolda Gardens and the Reynolda House Museum of American Art). Other sites of interest include the Horne Creek Historic Farm, Tanglewood Park golf course, the SciWorks educational facility, and SECCA, the Southeastern Center for Contemporary Art. The city's major sports and entertainment venues are organized in a group known as the Winston-Salem Entertainment-Sports Complex.
The Winston-Salem metropolitan area (MSA) has an estimated population of 490,159 according to the 2004 estimate by the U.S. Census Bureau. As of 2007, the combined statistical area (CSA) of Greensboro/Winston-Salem/High Point, the Piedmont Triad, has a population of 1,535,926, making it the 30th-largest metropolitan area in the USA.