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is a town located in the northeastern part of Erie County, New York, United States. The population was 26,123 at the 2000 census. Clarence is also the name of a postal district in the south part of the town with ZIP code 14031. It is named after the House of Clarence in England.
is in the northeast part of the county. The town is northeast of Buffalo. There are no incorporated villages within the town.
According to the United States Census Bureau, the town has a total area of 53.5 square miles (138.5 km²), of which, 53.4 square miles (138.3 km²) of it is land and 0.1 square miles (0.2 km²) of it (0.11%) is water.
The north border of the town is marked by Tonawanda Creek with Niagara County on the opposite bank.
New York State Route 5, called "Main Street" locally, passes across the south part of the town. NY Route 78, "Transit Road," marks the west town line. The eastern terminus of NY Route 324, "Sheridan Drive," is located in Clarence at the intersection of NY-5 and Thompson Road. The New York State Thruway (Interstate 90) is immediately south of the town.