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is a hamlet and census-designated place in the town of Huntington in Suffolk County on Long Island, New York, in the United States. As of the 2000 census, 14,533 people resided there.
Melville is home to the U.S. headquarters of several national and international corporations, including American Home Mortgage, Arrow Electronics, Chyron, Gentiva Health Services, Nikon Corporation, OSI Pharmaceuticals, Allion Healthcare, the Italian-food chain Sbarro, the medical and dental supply distributor Henry Schein, Bouchard Transportation and global staffing giant, Adecco (US Headquarters). In addition, significant operations of Manhattan-based, Estée Lauder are conducted there. Melville, is also the host of operations for many Fortune 500 companies, such as First Data
These headquarters and many other corporate and industrial centers are found on or near Route 110, which runs north to south through Huntington, Melville, and Amityville.
Around 2002 Swiss International Air Lines's North American headquarters moved from Melville to Uniondale, Town of Hempstead. The facility, the former Swissair North American headquarter site, was completed in 1995. Swissair intended to own, instead of lease, its headquarters site. It enlisted architect Richard Meier to design the Melville facility.