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is a city in the U.S. state of Ohio and the county seat of Guernsey County. The municipality is located in southeastern Ohio and is in the Appalachian Plateau of the Appalachian Mountains. At the time of the 2000 census, Cambridge was a city with 11,520 residents. It is the center of the Cambridge Micropolitan Statistical Area (as defined by the United States Census Bureau in 2003). Cambridge is well-known among glass collectors as being the location for the Cambridge Glass, Boyd Glass and Mosser Glass plants. The Cambridge area is also famous for its "S" shaped bridges, some of the first bridges ever constructed in the Northwest Territory. It is located adjacent to the intersection of I-70 and I-77, which the Ohio Department of Transportation proclaimed in 1969 was the world's largest interchange (in terms of land area).
In 1796 Col. Ebenezer Zane received funds to cut a road from Ohio to Kentucky. He responded by naming the first settlements in honor of Cambridge, Maryland. The land on which part of Cambridge stands was granted to Zaccheus Biggs and Zaccheus Beatty by the government in 1801. In 1806 another group of early settlers from the Isle of Guernsey in the English Channel of England pitched camp in Cambridge because the women in the party refused to move on.
Tom Orr is the current Mayor of Cambridge.
He replaces former Mayor Sam Salupo, who replaced the opponent of Tommy Orr's, Charles Schaub.