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is a city in Muskogee County, Oklahoma, United States. It is the county seat of Muskogee County, and home to Bacone College. The population was 38,310 at the 2000 census, making it the eleventh largest city in Oklahoma. Muskogee residents are called Okies from Muskogee (although some consider the term to be mildly disparaging).
According to the United States Census Bureau, the city has a total area of 38.8 square miles (100.4 km²), of which, 37.3 square miles (96.7 km²) of it is land and 1.4 square miles (3.7 km²) of it (3.69%) is water. Muskogee is near the confluence of the Arkansas River, Verdigris River and Grand River.
It is crossed by U.S. Route 62, U.S. Route 64, Oklahoma State Highway 2, Oklahoma State Highway 16 and Oklahoma State Highway 165.