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is a census-designated place (CDP) in York County, South Carolina, United States. The population was 3,061 at the 2000 census. The town of Lake Wylie, SC derives its name from Lake Wylie (the body of water), which was named after Dr. W. Gil Wylie in 1960.
Lake Wylie, South Carolina is located at along the shore of Lake Wylie, at (35.105973, -81.056978).
According to the United States Census Bureau, the CDP has a total area of 4.7 square miles (12.3 km²), of which, 3.5 square miles (9.0 km²) of it is land and 1.3 square miles (3.3 km²) of it (26.58%) is water.