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is a census-designated place (CDP) along the Saluda River in Anderson and Greenville counties in the U.S. state of South Carolina. The population was 4,684 at the 2000 census.
The Greenville County portion of Piedmont is part of the Greenville–Mauldin–Easley Metropolitan Statistical Area, while the Anderson County portion is part of the Anderson Metropolitan Statistical Area.
The town of Piedmont was created as the site for the Piedmont Manufacturing Company, which was organized in 1873 and began operation in 1876. This textile mill was one of the first large-scale cotton manufacturers in upstate South Carolina and had considerable influence on the development of other mills in the area.