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Wadmalaw Island is located generally to the southwest of Johns Island and more than halfway encircled by it. To the north it is bordered by Church Creek; to the northeast and east by Bohicket Creek; to the south by the North Edisto River; and to the west by the Bohicket Creek. The island's only connection to the mainland is via a bridge over Church Creek. The island is about 10 miles long by 6 miles wide. It has a land area of 108.502 km² (41.893 sq mi). The 2000 census reported a population of 2,611 persons, with the largest concentration in its only town of Rockville.