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is a city located in Brown County in the U.S. state of Wisconsin. As of the 2004 census estimate, the city had a total population of 22,875. De Pere is a suburb of Green Bay and is part of the Green Bay Metropolitan Statistical Area.
In 1671 French Jesuit explorer Père Claude-Jean Allouez founded the St. Francis Xavier Mission at the last set of rapids on the Fox River before entering the Bay of Green Bay. The site was known as Rapides Des Pères (rapids of the fathers) which became modern day De Pere.
Originally De Pere consisted of only the community on the east side of the river; however, in 1890 the community on the west side of the river was annexed into the City of De Pere.
St. Norbert College, which abuts the banks of the Fox River on the city's west side near the Claude Allouez Bridge, was founded by Norbertine Abbot Pennings in 1898.
A ticket for Powerball bought in De Pere won the jackpot in the September 5, 2007 drawing. The winner chose the $13.7 million cash option.